SCHEMBL7687599

SCHEMBL7687599

O=C1CCCCN1C(=O)N1CCCCC1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
MITF O75030 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPT P10636 3/20 0.41
KDM4E B2RXH2 3/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
THRB P10828 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
ALDH1A1 P00352 5/20 0.40
TP53 P04637 2/20 0.40
HSD17B10 Q99714 2/20 0.40
STAT6 P42226 1/20 0.40
TSHR P16473 1/20 0.38
BRD4 O60885 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5181091 0.98 LMNA (0.54) LMNAMITFSMN1; SMN2MAPTKDM4E
SCHEMBL131845 0.98 LMNA (0.54) LMNAMITFSMN1; SMN2MAPTKDM4E
SCHEMBL2594237 0.92 LMNA (0.64) LMNAMITFSMN1; SMN2MAPTKDM4E
SCHEMBL16451432 0.86 LMNA (0.44) LMNAMITFSMN1; SMN2MAPTKDM4E
SCHEMBL20474019 0.84 LMNA (0.55) LMNAMITFSMN1; SMN2MAPTKDM4E
SCHEMBL8379227 0.83 LMNA (0.54) LMNAMITFSMN1; SMN2MAPTKDM4E
SCHEMBL1238335 0.83 LMNA (0.54) LMNAMITFSMN1; SMN2MAPTKDM4E
SCHEMBL15233814 0.81 LMNA (0.44) LMNAMITFSMN1; SMN2MAPTKDM4E
SCHEMBL4059818 0.81 LMNA (0.52) LMNAMITFSMN1; SMN2MAPTKDM4E
SCHEMBL4062492 0.81 LMNA (0.52) LMNAMITFSMN1; SMN2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6451753-B2 CYCLIC CARBAMATE, LACTONOXY OR LACTAM STRUCTURE AND/OR OXIME ESTERS AND INERT POROUS CARRIER OF GIVEN SURFACE AREA; STORAGE STABLE SOLID, FREE-FLOWING FORM BASF AKTIENGESELLSCHAFT (DE) 2002-09-17 US disclosed
EP-0826025-B1 USE OF HETEROCYCLIC COMPOUNDS AS ACTIVATORS FOR INORGANIC PEROXY COMPOUNDS BASF AG (DE) 2000-03-01 EP disclosed
US-5972237-A USED AS COLD BLEACH ACTIVATORS OR OPTICAL BRIGHTENERS IN DETERGENTS, CLEANERS AND BLEACHES AND IN DISINFECTANTS BASF AKTIENGESELLSCHAFT (DE) 1999-10-26 US disclosed
EP-0826025-A1 USE OF HETEROCYCLIC COMPOUNDS AS ACTIVATORS FOR INORGANIC PEROXY COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1998-03-04 EP disclosed
WO-1996036686-A1 USE OF HETEROCYCLIC COMPOUNDS AS ACTIVATORS FOR INORGANIC PEROXY COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1996-11-21 WO disclosed