Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LDHA | P00338 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688048 | 0.84 | TP53 (0.50) | MAPTALDH1A1LDHATSHRHPGD | |
| SCHEMBL7683624 | 0.79 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1MAPTALDH1A1TSHR | |
| SCHEMBL25732097 | 0.75 | CYP19A1 (0.54) | HSP90AA1HSP90AB1MAPTALDH1A1TSHR | |
| SCHEMBL6797519 | 0.72 | TP53 (0.47) | MAPTALDH1A1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL7689245 | 0.71 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1ALDH1A1TSHRHPGD | |
| SCHEMBL7683993 | 0.70 | MAP1LC3B (0.40) | LDHALDHBMAP1LC3B | |
| SCHEMBL4430798 | 0.70 | TSHR (0.51) | HSP90AA1HSP90AB1MAPTALDH1A1TSHR | |
| SCHEMBL7681299 | 0.70 | TP53 (0.43) | MAPTALDH1A1LDHATSHRHPGD | |
| Hydrochloric Acid SCHEMBL7678966 | 0.70 | — | — | |
| SCHEMBL7683315 | 0.69 | ALPL (0.60) | HSP90AA1HSP90AB1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |