Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678313 | 0.72 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL7678114 | 0.71 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL12589465 | 0.68 | KDM4E (0.59) | — | |
| SCHEMBL19737586 | 0.68 | LMNA (0.59) | — | |
| SCHEMBL7676337 | 0.66 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL7676384 | 0.64 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL23903368 | 0.63 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL7678441 | 0.63 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL1762674 | 0.61 | LMNA (0.58) | CRHR1 | |
| SCHEMBL22643826 | 0.58 | AR (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | disclosed |
| US-6107301-A | PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| WO-1995010506-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-04-20 | — | — | WO | disclosed |