Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22702838 | 0.79 | ALDH1A1 (0.41) | RIPK1TNFNPSR1GAAKMT2A | |
| SCHEMBL14687910 | 0.79 | ALDH1A1 (0.41) | RIPK1TNFNPSR1GAAKMT2A | |
| SCHEMBL1362696 | 0.79 | RIPK1 (0.42) | RIPK1TNFNPSR1GAAKMT2A | |
| SCHEMBL16001119 | 0.79 | RIPK1 (0.42) | RIPK1TNFNPSR1GAAKMT2A | |
| SCHEMBL15026061 | 0.79 | ALDH1A1 (0.41) | RIPK1TNFNPSR1GAAKMT2A | |
| SCHEMBL25404225 | 0.77 | RIPK1 (0.38) | RIPK1TNFNPSR1GAAKMT2A | |
| SCHEMBL10159151 | 0.77 | NPSR1 (0.41) | RIPK1TNFNPSR1GAAKMT2A | |
| SCHEMBL13799221 | 0.77 | RIPK1 (0.38) | RIPK1TNFNPSR1GAAKMT2A | |
| SCHEMBL3641150 | 0.77 | ALDH1A1 (0.38) | RIPK1TNFNPSR1GAAKMT2A | |
| SCHEMBL10471424 | 0.76 | RIPK1 (0.37) | RIPK1TNFNPSR1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476027-B1 | N-hydroxy 4-sulfonyl butanamide compounds | MONSANTO COMPANY | 2002-11-05 | — | — | US | claimed |
| EP-0983258-A4 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO CO (US) | 2001-01-17 | — | — | EP | claimed |
| EP-0983258-A1 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO COMPANY (US) | 2000-03-08 | — | — | EP | claimed |
| WO-1998039316-A1 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | claimed |
| US-6476027-B1 | N-hydroxy 4-sulfonyl butanamide compounds | MONSANTO COMPANY | 2002-11-05 | — | — | US | disclosed |
| EP-0983258-A4 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO CO (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-0983258-A1 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO COMPANY (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998039316-A1 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |