Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.51 |
| ▸ | FNTB | P49356 | 6/20 | 0.51 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683557 | 0.86 | FNTA (0.50) | FNTAFNTBPGGT1BNSD2TBK1 | |
| SCHEMBL7681980 | 0.85 | FNTA (0.48) | FNTAFNTBPGGT1B | |
| SCHEMBL7690190 | 0.85 | FNTA (0.48) | FNTAFNTBPGGT1B | |
| SCHEMBL7622383 | 0.84 | FNTA (0.49) | FNTAFNTBPGGT1BNSD2TBK1 | |
| SCHEMBL7689564 | 0.83 | FNTA (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL7648190 | 0.83 | FNTA (0.55) | FNTAFNTBPGGT1BNSD2TBK1 | |
| SCHEMBL7681543 | 0.83 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL7687530 | 0.82 | FNTA (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL7683740 | 0.81 | FNTA (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL7681530 | 0.81 | FNTA (0.43) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052363-A1 | Inhibitors of prenyl-protein transferase | DINSMORE CHRISTOPHER J (US) | 2002-05-02 | — | — | US | claimed |
| WO-2001060369-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-08-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052363-A1 | Inhibitors of prenyl-protein transferase | FNTA, FNTB, PTAR1 | FNTA 1/4885FNTB 2/4885PGGT1B 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.