Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.50 |
| ▸ | FNTB | P49356 | 5/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688045 | 0.86 | FNTA (0.51) | FNTAFNTBPGGT1BNSD2TBK1 | |
| SCHEMBL7690275 | 0.85 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL7622383 | 0.85 | FNTA (0.49) | FNTAFNTBPGGT1BNSD2TBK1 | |
| SCHEMBL7685750 | 0.85 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL7683732 | 0.84 | FNTA (0.44) | FNTAFNTBPGGT1B | |
| SCHEMBL7648190 | 0.83 | FNTA (0.55) | FNTAFNTBPGGT1BNSD2TBK1 | |
| SCHEMBL7689759 | 0.83 | FNTA (0.46) | FNTAFNTBPGGT1B | |
| SCHEMBL7690256 | 0.82 | FNTA (0.42) | FNTAFNTBPGGT1BFFAR4 | |
| SCHEMBL7688311 | 0.81 | FNTA (0.42) | FNTAFNTBPGGT1BFFAR4 | |
| SCHEMBL7690628 | 0.81 | FNTA (0.42) | FNTAFNTBPGGT1BFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052363-A1 | Inhibitors of prenyl-protein transferase | DINSMORE CHRISTOPHER J (US) | 2002-05-02 | — | — | US | claimed |
| US-20020052363-A1 | Inhibitors of prenyl-protein transferase | DINSMORE CHRISTOPHER J (US) | 2002-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052363-A1 | Inhibitors of prenyl-protein transferase | FNTA, FNTB, PTAR1 | FNTA 1/4885FNTB 2/4885PGGT1B 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.