Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | GAA | P10253 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 9/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643173 | 0.90 | ALDH1A1 (0.69) | ALDH1A1KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL6983821 | 0.87 | HCRTR1 (0.76) | ALDH1A1KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL3985463 | 0.87 | KDM4E (0.71) | ALDH1A1KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL16732481 | 0.87 | KDM4E (0.71) | ALDH1A1KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL830378 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL4077176 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL3283431 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL829961 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL16943501 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL3011731 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4ERAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |