Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 6/20 | 0.71 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8708638 | 0.89 | NR1H3 (0.59) | NR1H3NR1H2MEN1KMT2ALMNA | |
| SCHEMBL6676139 | 0.87 | MEN1 (0.68) | NR1H3NR1H2MEN1KMT2AHTT | |
| SCHEMBL6968611 | 0.87 | G6PD (0.59) | NR1H3NR1H2MEN1KMT2AHTT | |
| SCHEMBL7688170 | 0.84 | PDE4B (0.57) | NR1H3NR1H2 | |
| SCHEMBL8707692 | 0.83 | NR1H3 (0.53) | NR1H3NR1H2MEN1KMT2ALMNA | |
| SCHEMBL8713399 | 0.83 | PDE4B (0.56) | NR1H3NR1H2 | |
| SCHEMBL17326663 | 0.83 | MEN1 (0.53) | NR1H3NR1H2MEN1KMT2ALMNA | |
| SCHEMBL2578102 | 0.83 | NR1H3 (0.52) | NR1H3NR1H2MEN1KMT2AHTT | |
| SCHEMBL4256269 | 0.83 | NR1H3 (0.52) | NR1H3NR1H2MEN1KMT2AHTT | |
| SCHEMBL4250774 | 0.83 | NR1H3 (0.56) | NR1H3NR1H2MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124375-A | Substituted phthalimides for regulating the growth of plants | MONSANTO COMPANY (US) | 1978-11-07 | — | — | US | claimed |
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |
| US-4124375-A | Substituted phthalimides for regulating the growth of plants | MONSANTO COMPANY (US) | 1978-11-07 | — | — | US | disclosed |