Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 2/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.52 |
| ▸ | PDE4A | P27815 | 6/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707476 | 0.92 | PDE4B (0.47) | NR1H3NR1H2PDE4BPDE4APDE4C | |
| SCHEMBL7688170 | 0.86 | PDE4B (0.57) | NR1H3NR1H2PDE4BPDE4APDE4C | |
| SCHEMBL8713399 | 0.85 | PDE4B (0.56) | NR1H3NR1H2PDE4BPDE4APDE4C | |
| SCHEMBL7689616 | 0.83 | NR1H3 (0.71) | NR1H3NR1H2MEN1KMT2ALMNA | |
| SCHEMBL8713095 | 0.81 | PDE4B (0.47) | NR1H3NR1H2PDE4BPDE4APDE4C | |
| SCHEMBL8713937 | 0.81 | PDE4B (0.47) | NR1H3NR1H2PDE4BPDE4APDE4C | |
| SCHEMBL8710571 | 0.81 | PDE4B (0.42) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8711275 | 0.80 | RAB9A (0.57) | NR1H3NR1H2PDE4BPDE4APDE4C | |
| SCHEMBL8707317 | 0.80 | NR1H3 (0.51) | NR1H3NR1H2PDE4BPDE4APDE4C | |
| SCHEMBL8710486 | 0.79 | PDE4B (0.44) | NR1H3NR1H2PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042666-A1 | NOVEL 3,4-DIALKOXYPHENYL DERIVATIVES AND THE USE THEREOF | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1998-10-01 | — | — | WO | disclosed |