Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494199 | 0.89 | CYP4F2 (0.44) | CYP4F2CYP4A11POLBHSP90AB1SLC7A5 | |
| SCHEMBL7221306 | 0.83 | ALDH1A1 (0.41) | POLBSMN1; SMN2KDM4EKMT2AALDH1A1 | |
| SCHEMBL7228110 | 0.79 | AKR1B1 (0.40) | SMN1; SMN2KDM4EKMT2ATP53ALDH1A1 | |
| SCHEMBL1443509 | 0.76 | CYP4F2 (0.41) | CYP4F2CYP4A11POLBHSP90AB1SMN1; SMN2 | |
| SCHEMBL1234999 | 0.70 | CYP4F2 (0.39) | CYP4F2CYP4A11HSP90AB1SMN1; SMN2KDM4E | |
| SCHEMBL2687097 | 0.69 | EGFR (0.45) | CYP4F2CYP4A11POLBHSP90AB1SLC7A5 | |
| SCHEMBL16390828 | 0.69 | MAPT (0.43) | POLBSMN1; SMN2KDM4EKMT2AALDH1A1 | |
| SCHEMBL5841237 | 0.69 | MCL1 (0.37) | POLBSMN1; SMN2KDM4EKMT2AALDH1A1 | |
| SCHEMBL8026225 | 0.68 | CA1 (0.45) | CYP4F2CYP4A11POLBSMN1; SMN2KDM4E | |
| Methyl Alcohol SCHEMBL3396251 | 0.67 | ALDH1A1 (0.61) | CYP4F2CYP4A11HSP90AB1SLC7A5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337423-B1 | BIND TO VOLTAGE-GATED SODIUM ION CHANNELS TO MODULATE ACTIVITY | ADVANCED MEDICINE, INC. | 2002-01-08 | — | — | US | disclosed |