Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688201 | 0.89 | CYP4F2 (0.40) | CYP4F2CYP4A11HSP90AB1SLC7A5ALDH1A1 | |
| SCHEMBL1443509 | 0.79 | CYP4F2 (0.41) | CYP4F2CYP4A11HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL1234999 | 0.76 | CYP4F2 (0.39) | CYP4F2CYP4A11HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL27322685 | 0.76 | POLB (0.38) | ALDH1A1KDM4ESMN1; SMN2POLBKMT2A | |
| SCHEMBL8647169 | 0.73 | AKR1B1 (0.48) | KDM4EPOLBGAAHSD17B10MAPT | |
| Methyl Alcohol SCHEMBL3396251 | 0.72 | ALDH1A1 (0.61) | CYP4F2CYP4A11HSP90AB1SLC7A5ALDH1A1 | |
| SCHEMBL12400239 | 0.72 | SLC7A5 (0.68) | CYP4F2CYP4A11HSP90AB1SLC7A5ALDH1A1 | |
| SCHEMBL1554320 | 0.71 | KDM4E (0.53) | CYP4F2CYP4A11HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL68310 | 0.71 | KDM4E (0.56) | CYP4F2CYP4A11ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8153544 | 0.71 | KDM4E (0.49) | CYP4F2CYP4A11HSP90AB1SLC7A5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638075-B1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| US-5677322-A | THERAPY FOR AGING, DIABETES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |