Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 17/20 | 0.36 |
| ▸ | KDR | P35968 | 8/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | TEK | Q02763 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688304 | 1.00 | PDGFRA (0.37) | PDGFRAMETKDRAURKATEK | |
| SCHEMBL7692700 | 0.92 | LPAR1 (0.33) | PDGFRAMETKDR | |
| SCHEMBL7692701 | 0.92 | LPAR1 (0.33) | PDGFRAMETKDR | |
| SCHEMBL7693295 | 0.90 | BRAF (0.34) | KDR | |
| SCHEMBL7691909 | 0.89 | KDR (0.36) | PDGFRAMETKDRAURKATEK | |
| SCHEMBL7691911 | 0.89 | KDR (0.36) | PDGFRAMETKDRAURKATEK | |
| SCHEMBL6479054 | 0.88 | LPAR1 (0.34) | METKDR | |
| SCHEMBL6479065 | 0.88 | LPAR1 (0.34) | METKDR | |
| SCHEMBL7245302 | 0.87 | OPRD1 (0.39) | — | |
| SCHEMBL7245309 | 0.87 | OPRD1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |