Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 11/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | TEK | Q02763 | 2/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 5/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691911 | 1.00 | KDR (0.36) | KDRPDGFRAMETCYP3A4PRKACG | |
| SCHEMBL7688980 | 0.92 | KDR (0.34) | KDRPDGFRAMETMEN1MAPT | |
| SCHEMBL7688979 | 0.92 | KDR (0.34) | KDRPDGFRAMETMEN1MAPT | |
| SCHEMBL7691026 | 0.90 | KDR (0.33) | KDRPDGFRACYP3A4MEN1MAPT | |
| SCHEMBL7691028 | 0.90 | KDR (0.33) | KDRPDGFRACYP3A4MEN1MAPT | |
| SCHEMBL6491040 | 0.89 | CTSV (0.33) | KDRPDGFRAMETMEN1MAPT | |
| SCHEMBL6491044 | 0.89 | CTSV (0.33) | KDRPDGFRAMETMEN1MAPT | |
| SCHEMBL7688302 | 0.89 | PDGFRA (0.37) | KDRPDGFRAMETCYP3A4PRKACG | |
| SCHEMBL7688304 | 0.89 | PDGFRA (0.37) | KDRPDGFRAMETCYP3A4PRKACG | |
| SCHEMBL7036429 | 0.88 | KMT2A (0.41) | MEN1MAPTKMT2ACTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |