Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12608407 | 0.83 | HPGD (0.65) | HPGDDRD2DRD4DRD3RAB9A | |
| SCHEMBL28958764 | 0.81 | HPGD (0.58) | HPGDDRD2DRD4DRD3RAB9A | |
| SCHEMBL23374717 | 0.81 | HPGD (0.58) | HPGDDRD2DRD4DRD3RAB9A | |
| SCHEMBL7687826 | 0.81 | HPGD (0.62) | HPGDDRD2DRD4DRD3RAB9A | |
| SCHEMBL14416100 | 0.80 | HPGD (0.64) | HPGDDRD2DRD4DRD3RAB9A | |
| SCHEMBL13510002 | 0.78 | HPGD (0.59) | HPGDDRD2DRD4DRD3RAB9A | |
| SCHEMBL10864066 | 0.78 | HPGD (0.55) | HPGDDRD2DRD4DRD3RAB9A | |
| SCHEMBL102463 | 0.77 | LMNA (0.52) | HPGDDRD2DRD4DRD3RAB9A | |
| SCHEMBL7695158 | 0.77 | HPGD (0.54) | HPGDDRD2DRD4DRD3RAB9A | |
| SCHEMBL28958745 | 0.76 | HPGD (0.56) | HPGDDRD2DRD4DRD3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380187-B2 | FUNGICIDES | YU DINGWEI TIM (US) | 2002-04-30 | — | — | US | disclosed |
| US-6281217-B2 | ANTIFUNGAL ACTIVITY AGAINST A VARIETY OF FUNGI INCLUDING STRAINS WHICH HAVE PROVEN TO BE RESISTANT TO TREATMENT WITH KNOWN ANTIFUNGAL AGENTS SUCH AS FLUCONAZOLE. | YU DINGWEI TIM (US) | 2001-08-28 | — | — | US | disclosed |