Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.43 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.37 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.37 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.37 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.37 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.37 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.37 |
| ▸ | CACNA2D4 | Q7Z3S7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688278 | 0.98 | SLC10A2 (0.43) | SLC10A2CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL8459638 | 0.91 | MEN1 (0.36) | SLC10A2ALDH1A1MAPTGSK3BABCG2 | |
| SCHEMBL7683540 | 0.91 | SLC10A2 (0.41) | SLC10A2CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL8459158 | 0.89 | MAPT (0.35) | SLC10A2ALDH1A1MAPTGSK3BABCG2 | |
| SCHEMBL7681647 | 0.85 | SLC10A2 (0.41) | SLC10A2CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL7681637 | 0.83 | SLC10A2 (0.44) | SLC10A2CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL7688481 | 0.80 | SLC10A2 (0.42) | SLC10A2CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL7683887 | 0.79 | SLC10A2 (0.42) | SLC10A2CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL7811976 | 0.79 | SLC10A2 (0.51) | SLC10A2CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL7685844 | 0.78 | SLC10A2 (0.42) | SLC10A2CACNB4CACNA1ACACNA1GCACNG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403606-B1 | ANTIINFLAMMATORY, ANTIARTHRITIS, A DRUG FOR INHIBITING BONE RESORPTION, IMMUNOSUPPRESSANT | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2002-06-11 | — | — | US | disclosed |
| US-6046189-A | ANTI-INFLAMMATORY DRUG, PARTICULARLY, A DRUG FOR PREVENTING OR TREATING ARTHRITIS, A DRUG FOR INHIBITING BONE RESORPTION, IMMUNOSUPPRESSANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-04-04 | — | — | US | disclosed |