Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366657 | 0.91 | SLC10A2 (0.49) | SLC10A2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL607272 | 0.91 | SLC10A2 (0.49) | SLC10A2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7817907 | 0.86 | SLC10A2 (0.46) | SLC10A2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8140255 | 0.86 | ALDH1A1 (0.48) | SLC10A2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7819869 | 0.85 | SLC10A2 (0.47) | SLC10A2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7818008 | 0.85 | ALDH1A1 (0.53) | SLC10A2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7820868 | 0.85 | SLC10A2 (0.51) | SLC10A2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8628406 | 0.85 | ALDH1A1 (0.44) | SLC10A2TUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL7819467 | 0.85 | SLC10A2 (0.46) | SLC10A2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7820071 | 0.84 | SLC10A2 (0.46) | SLC10A2TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608870-B1 | Quinoline or quinazoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0634169-B1 | Quinoline or quinazoline derivatives and their use in the manufacture of a medicament for the treatment of osteoporosis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-01-05 | — | — | EP | disclosed |
| US-5932592-A | ETHYL 4-(3,4-DIMETHOXYPHENYL)-6,7-DIMETHOXY-2-(1,2,4-TRIAZOLE-1-YLME THYL)QUINOLINE-3-CARBOXYLATE; ANTIINFLAMMATORY AND ANTIARTHRITIC AGENT | TAKEDA CHEMICAL IND., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| US-5852039-A | Pharmaceutical composition containing quinoline or quinazoline derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5770602-A | REACTING QUIONOZOLINE OR QUINOLINE DERIVATIVES CONTAINING LEAVING GROUPS WITH NITROGEN CONTAINING UNSATURATED CYCLIC GROUP WHICH MAY BE SUBSTITUTED OR UNSUBSTITUTED; ANTIARTHRITIC AGENT | TAKEDA CHEMICAL INDUSTRIES (JP) | 1998-06-23 | — | — | US | disclosed |
| US-5719157-A | OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5436247-A | Antiinflammatory agents or antiarthritic agents | TAKEDA CHEMICAL INDUSTRIES (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0634169-A1 | Pharmaceutical composition containing quinoline or quinazoline derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0608870-A1 | Quinoline or quinazoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-03 | — | — | EP | disclosed |