Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 16/20 | 0.51 |
| ▸ | NOS1 | P29475 | 16/20 | 0.51 |
| ▸ | NOS2 | P35228 | 11/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695517 | 0.89 | NOS1 (0.51) | NOS3NOS1NOS2 | |
| SCHEMBL7695105 | 0.87 | NOS3 (0.46) | NOS3NOS1NOS2 | |
| SCHEMBL7690815 | 0.87 | NOS3 (0.46) | NOS3NOS1NOS2 | |
| SCHEMBL7696490 | 0.86 | NOS3 (0.48) | NOS3NOS1NOS2 | |
| SCHEMBL7697635 | 0.85 | NOS3 (0.53) | NOS3NOS1NOS2 | |
| SCHEMBL7690814 | 0.84 | QRFPR (0.50) | NOS3NOS1NOS2 | |
| SCHEMBL7693951 | 0.84 | NOS3 (0.49) | NOS3NOS1NOS2 | |
| SCHEMBL7690788 | 0.84 | QRFPR (0.46) | NOS3NOS1NOS2 | |
| SCHEMBL7694859 | 0.83 | QRFPR (0.46) | NOS3NOS1NOS2 | |
| SCHEMBL7691757 | 0.82 | NOS3 (0.51) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020511-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2002-03-14 | — | — | WO | claimed |