Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682341 | 0.88 | L3MBTL1 (0.44) | GAAMGAMSIMGAM2TOP2A | |
| SCHEMBL11288753 | 0.82 | GAA (0.45) | GAAMGAMSIMGAM2TOP2A | |
| SCHEMBL7309740 | 0.81 | GAA (0.52) | GAAMGAMSIMGAM2TOP2A | |
| SCHEMBL13250492 | 0.77 | GAA (0.46) | GAAMGAMSIMGAM2TOP2A | |
| SCHEMBL3987200 | 0.77 | GAA (0.46) | GAAMGAMSIMGAM2TOP2A | |
| SCHEMBL3209626 | 0.75 | GAA (0.45) | GAAMGAMSIMGAM2TOP2A | |
| SCHEMBL29023037 | 0.75 | GAA (0.45) | GAAMGAMSIMGAM2TOP2A | |
| SCHEMBL11074412 | 0.74 | GAA (0.48) | GAAMGAMSIMGAM2TOP2A | |
| Hydrochloric Acid SCHEMBL10499779 | 0.74 | GAA (0.43) | GAAMGAMSIMGAM2TOP2A | |
| SCHEMBL11237465 | 0.74 | CYP1A2 (0.48) | GAAMGAMSIMGAM2TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455538-B1 | SODIUM CHANNEL MODULATORS; BRAIN AND NERVOUS SYSTEM DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-09-24 | — | — | US | disclosed |