SCHEMBL11237465

SCHEMBL11237465

CCOC(=O)CCNC(C)CN

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
GAA P10253 2/20 0.43
MGAM O43451 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
TRPA1 O75762 1/20 0.36
TOP2A P11388 1/20 0.36
SMYD3 Q9H7B4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11233700 0.86 ALDH1A1 (0.40) CYP1A2L3MBTL1ALDH1A1KDM4ETOP2A
SCHEMBL3987200 0.85 GAA (0.46) CYP1A2GAAMGAMSIMGAM2
SCHEMBL3209626 0.84 GAA (0.45) CYP1A2GAAMGAMSIMGAM2
SCHEMBL11239070 0.83 TSHR (0.46) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL13151214 0.83 CYP1A2 (0.42) CYP1A2GAAMGAMSIMGAM2
SCHEMBL7309740 0.83 GAA (0.52) CYP1A2GAAMGAMSIMGAM2
Hydrochloric Acid SCHEMBL10499779 0.82 GAA (0.43) CYP1A2GAAMGAMSIMGAM2
SCHEMBL2039271 0.81 GAA (0.46) CYP1A2GAAMGAMSIMGAM2
SCHEMBL11239489 0.80 LMNA (0.43) ALDH1A1
SCHEMBL21175294 0.79 GAA (0.41) CYP1A2GAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315846-A FUNGICIDES TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1982-02-16 US disclosed
EP-0037861-A1 Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1981-10-21 EP disclosed