Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680831 | 0.82 | DRD2 (0.64) | KDM4EALDH1A1DRD2GAAMEN1 | |
| SCHEMBL3414057 | 0.81 | KDM4E (0.77) | KDM4EALDH1A1TSHRGAATDP1 | |
| SCHEMBL6131905 | 0.81 | DRD2 (0.63) | KDM4EALDH1A1DRD2GAAMEN1 | |
| Hydrochloric Acid SCHEMBL6132064 | 0.81 | DRD2 (0.63) | KDM4EALDH1A1DRD2GAAMEN1 | |
| Bromide SCHEMBL6132084 | 0.80 | DRD2 (0.61) | KDM4EALDH1A1DRD2GAAMEN1 | |
| SCHEMBL3377350 | 0.78 | GAA (0.67) | KDM4EALDH1A1GAATDP1LMNA | |
| SCHEMBL5667126 | 0.77 | DRD2 (0.47) | KDM4EDRD2HRH3MEN1KMT2A | |
| SCHEMBL4150936 | 0.77 | GAA (0.69) | KDM4EALDH1A1GAALMNAHTT | |
| SCHEMBL21709064 | 0.75 | TAAR1 (0.58) | KDM4EALDH1A1TSHRDRD2GAA | |
| SCHEMBL7379184 | 0.73 | HRH3 (0.59) | KDM4EALDH1A1TSHRACHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479495-B1 | SIMULTANEOUSLY TREATING DEPRESSION AND MEMORY DYSFUNCTION IN MAMMALS SUFFERING FROM MEMORY DYSFUNCTION AND DEPRESSION | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |