Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 3/20 | 0.33 |
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688980 | 1.00 | KDR (0.34) | KDRPDGFRACTSVCTSLLPAR1 | |
| SCHEMBL6491044 | 0.95 | CTSV (0.33) | KDRPDGFRACTSVCTSLLPAR1 | |
| SCHEMBL6491040 | 0.95 | CTSV (0.33) | KDRPDGFRACTSVCTSLLPAR1 | |
| SCHEMBL7691909 | 0.92 | KDR (0.36) | KDRPDGFRACTSVCTSLMAPT | |
| SCHEMBL7691911 | 0.92 | KDR (0.36) | KDRPDGFRACTSVCTSLMAPT | |
| SCHEMBL7691026 | 0.92 | KDR (0.33) | KDRPDGFRAMAPTMEN1NPC1 | |
| SCHEMBL7691028 | 0.92 | KDR (0.33) | KDRPDGFRAMAPTMEN1NPC1 | |
| SCHEMBL7692701 | 0.89 | LPAR1 (0.33) | KDRPDGFRALPAR1LPAR5MET | |
| SCHEMBL7692700 | 0.89 | LPAR1 (0.33) | KDRPDGFRALPAR1LPAR5MET | |
| SCHEMBL6478658 | 0.85 | MEN1 (0.39) | CTSVCTSLMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |