Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7592103 | 1.00 | SLC9A1 (0.40) | SLC9A1ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL6984509 | 0.93 | ALDH1A1 (0.41) | SLC9A1ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL7677811 | 0.93 | ALDH1A1 (0.41) | SLC9A1ALDH1A1MAPTTSHRHPGD | |
| SCHEMBL6984952 | 0.93 | ALDH1A1 (0.41) | SLC9A1ALDH1A1MAPTTSHRHPGD | |
| Hydrochloric Acid SCHEMBL7592478 | 0.92 | ALDH1A1 (0.40) | SLC9A1ALDH1A1MAPTTSHRHPGD | |
| Hydrochloric Acid SCHEMBL7594196 | 0.92 | ALDH1A1 (0.40) | SLC9A1ALDH1A1MAPTTSHRHPGD | |
| Hydrochloric Acid SCHEMBL7696213 | 0.92 | ALDH1A1 (0.40) | SLC9A1ALDH1A1MAPTTSHRHPGD | |
| Fumaric Acid SCHEMBL7591644 | 0.91 | SLC9A1 (0.38) | SLC9A1ALDH1A1MAPTTSHRHPGD | |
| Fumaric Acid SCHEMBL7592486 | 0.91 | SLC9A1 (0.38) | SLC9A1ALDH1A1MAPTTSHRHPGD | |
| Oxalic Acid SCHEMBL7595700 | 0.84 | MEN1 (0.41) | SLC9A1ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451789-B1 | CENTRAL NERVOUS SYSTEM DISORDERS; COGNITION ACTIVATORS | LES LABORTOIRES SERVIER (FR) | 2002-09-17 | — | — | US | disclosed |
| US-6323222-B1 | COGNITION ACTIVATORS, ALZHEIMER*S DISEASE AND ENZYME INHIBITORS | ADIR ET COMPAGNIE (FR) | 2001-11-27 | — | — | US | disclosed |