Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.65 |
| ▸ | CTSK | P43235 | 9/20 | 0.65 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522969 | 0.95 | CTSS (0.56) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL20866077 | 0.91 | CTSS (0.73) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL21068130 | 0.91 | CTSS (0.73) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL7152899 | 0.89 | CTSS (0.67) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL7518690 | 0.88 | CA2 (0.53) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2928795 | 0.88 | CTSS (0.78) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL7513132 | 0.86 | CA2 (0.52) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL7517184 | 0.86 | CTSS (0.53) | CTSSCTSKCTSBCTSLCA2 | |
| SCHEMBL2929067 | 0.85 | CTSS (0.74) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL14403609 | 0.85 | CTSS (0.65) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002026697-A2 | AROMATIC DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | PHARMACOR, INC. (CA) | 2002-04-04 | — | — | WO | disclosed |