SCHEMBL7689145

SCHEMBL7689145

CC(C)(C)N[Si](C)(C)OC1CCc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.50
PDPK1 O15530 1/20 0.42
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
BCHE P06276 1/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
ACHE P22303 1/20 0.37
ADRA1A P35348 1/20 0.37
HTR6 P50406 1/20 0.37
ANO1 Q5XXA6 2/20 0.36
GPR84 Q9NQS5 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CYP11B2 P19099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22056586 0.81 IDO1 (0.53) IDO1PDPK1MAOAMAOBBCHE
SCHEMBL16247717 0.72 IDO1 (0.53) IDO1PDPK1GPR84CA1CA2
SCHEMBL7151476 0.72 SLC6A2 (0.34)
SCHEMBL809619 0.71 IDO1 (0.62) IDO1PDPK1ADRA2BADRA2CADRA1A
SCHEMBL447420 0.71 IDO1 (0.66) IDO1PDPK1MAOAMAOBBCHE
SCHEMBL21300294 0.71 IDO1 (0.66) IDO1PDPK1MAOAMAOBBCHE
SCHEMBL14209228 0.71 IDO1 (0.66) IDO1PDPK1MAOAMAOBBCHE
SCHEMBL376248 0.70 IDO1 (0.70) IDO1PDPK1GPR84CYP11B2
SCHEMBL23259048 0.69 IDO1 (0.53) IDO1PDPK1ADRA2BADRA2CADRA1A
SCHEMBL29457668 0.69 IDO1 (0.49) IDO1PDPK1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1178996-A1 METAL COMPLEXES CONTAINING BRIDGING HETEROATOM FOR OLEFIN-POLYMERIZATION-PROCESS THE DOW CHEMICAL COMPANY (US) 2002-02-13 EP disclosed
WO-2000069870-A1 METAL COMPLEXES CONTAINING BRIDGING HETEROATOM FOR OLEFIN-POLYMERIZATION-PROCESS THE DOW CHEMICAL COMPANY (US) 2000-11-23 WO disclosed