SCHEMBL22056586

SCHEMBL22056586

CC(C)(C)[Si](C)(C)OC1CCc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.53
PDPK1 O15530 1/20 0.41
GPR84 Q9NQS5 1/20 0.36
CYP11B2 P19099 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
SIGMAR1 Q99720 1/20 0.36
BCHE P06276 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
ACHE P22303 1/20 0.36
ADRA1A P35348 1/20 0.36
HTR6 P50406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7689145 0.81 IDO1 (0.50) IDO1PDPK1GPR84CYP11B2MAOA
SCHEMBL20270050 0.80 HTR2A (0.43) IDO1HTR2AHTR2CHTR2B
SCHEMBL7197862 0.79 IDO1 (0.31) IDO1
SCHEMBL28527403 0.79 IDO1 (0.31) IDO1
SCHEMBL227332 0.79 SLC6A4 (0.41) IDO1HTR2AHTR2CHTR2B
SCHEMBL9277471 0.77 FFAR1 (0.38) IDO1HTR2AHTR2CHTR2BADRA2B
SCHEMBL9277476 0.77 FFAR1 (0.38) IDO1HTR2AHTR2CHTR2BADRA2B
SCHEMBL17768564 0.77 FFAR1 (0.40)
SCHEMBL20269757 0.77 ALDH1A1 (0.31)
SCHEMBL1895008 0.77 STS (0.33) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10669363-B2 Catalyst composition for synthesizing olefin copolymer and method for preparing olefin copolymer LG CHEM, LTD. (KR) 2020-06-02 US disclosed