Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491623 | 0.83 | KDM4E (0.40) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL8683752 | 0.83 | KDM4E (0.40) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL7867052 | 0.79 | TYK2 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL7552255 | 0.78 | TSHR (0.36) | SLC6A2SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL7552251 | 0.78 | TSHR (0.36) | SLC6A2SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL8491225 | 0.77 | CACNA1B (0.39) | KCNH2 | |
| SCHEMBL8491218 | 0.77 | CACNA1B (0.39) | KCNH2 | |
| SCHEMBL8754729 | 0.75 | PTGDR2 (0.35) | — | |
| SCHEMBL7554590 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1L3MBTL1KMT2A | |
| SCHEMBL7554588 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020045551-A1 | 4-benzoyl isoxazoles derivatives and their use as herbicides | MUSIL TIBOR (GB) | 2002-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045551-A1 | 4-benzoyl isoxazoles derivatives and their use as herbicides | CBR3, CBR1, GLRA3 | PTK2 3989/4885SMN1; SMN2 3433/4885SLC6A2 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.