SCHEMBL7689154

SCHEMBL7689154

C(=C(c1ccccc1)c1ccccc1)c1ccc(Nc2ccc(N(c3ccccc3)c3ccccc3)cc2)c(-c2ccc(-c3c4ccccc4c(C=C(c4ccccc4)c4ccccc4)c4ccccc34)cc2)c1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7686626 0.86
SCHEMBL2214749 0.84 KDM1A (0.33)
SCHEMBL2211757 0.84 PTGS2 (0.41) PTGS2
SCHEMBL6478736 0.83 CYP19A1 (0.35) PTGS2
SCHEMBL2210237 0.81 ALDH1A1 (0.34) PTGS2
SCHEMBL2208319 0.81 ANPEP (0.30)
SCHEMBL2085035 0.79 CYP19A1 (0.44) PTGS2
SCHEMBL12774521 0.78 CYP19A1 (0.42) PTGS2
SCHEMBL9971838 0.78 CYP19A1 (0.42) PTGS2
SCHEMBL9971759 0.76 CYP19A1 (0.44) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1195422-A1 THIN FILM EL DEVICE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-04-10 EP claimed
EP-1195422-A1 THIN FILM EL DEVICE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-04-10 EP disclosed