Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR1D | P28221 | 3/20 | 0.47 |
| ▸ | HTR1B | P28222 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
| ▸ | HTR1F | P30939 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689207 | 0.88 | HTR6 (0.53) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL7689209 | 0.80 | HTR6 (0.60) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL2226181 | 0.76 | NPSR1 (0.60) | NPSR1L3MBTL1MAPTPFKFB3PFKFB4 | |
| Hydrochloric Acid SCHEMBL6712744 | 0.75 | NPSR1 (0.59) | NPSR1L3MBTL1MAPTPFKFB3PFKFB4 | |
| SCHEMBL6980951 | 0.74 | HTR6 (0.80) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL6968303 | 0.72 | GAA (0.62) | HTR6L3MBTL1MAPTSIRT6 | |
| SCHEMBL1548591 | 0.70 | NPSR1 (0.62) | HTR6NPSR1L3MBTL1PFKFB3PFKFB4 | |
| SCHEMBL6980956 | 0.67 | HTR6 (0.77) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL3219783 | 0.67 | HTR6 (0.54) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL6981823 | 0.67 | HTR6 (0.80) | HTR6HTR1AHTR1DHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423717-B1 | NERVOUS SYSTEM DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-07-23 | — | — | US | disclosed |