Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689686 | 0.89 | ALDH1A1 (0.66) | ALDH1A1GAASMN1; SMN2LMNAMAPT | |
| SCHEMBL7682946 | 0.84 | ALDH1A1 (0.61) | ALDH1A1GAASMN1; SMN2POLBLMNA | |
| SCHEMBL7678997 | 0.82 | ALDH1A1 (0.59) | ALDH1A1GAASMN1; SMN2POLBLMNA | |
| SCHEMBL7682909 | 0.82 | ALDH1A1 (0.61) | ALDH1A1GAASMN1; SMN2POLBLMNA | |
| SCHEMBL7689683 | 0.81 | ALDH1A1 (0.58) | ALDH1A1GAASMN1; SMN2POLBLMNA | |
| SCHEMBL7683121 | 0.79 | ALDH1A1 (0.60) | ALDH1A1GAASMN1; SMN2POLBLMNA | |
| SCHEMBL7689688 | 0.75 | ALDH1A1 (0.67) | ALDH1A1GAASMN1; SMN2POLBLMNA | |
| SCHEMBL8121462 | 0.75 | ALDH1A1 (0.38) | ALDH1A1GAASMN1; SMN2POLBLMNA | |
| SCHEMBL7680981 | 0.66 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2POLBMAPTKDM4E | |
| SCHEMBL20016247 | 0.62 | ALDH1A1 (0.46) | ALDH1A1GAASMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |