Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128288 | 0.77 | ALDH1A1 (0.39) | ALDH1A1GAASMN1; SMN2IDO1FFAR4 | |
| SCHEMBL7682946 | 0.73 | ALDH1A1 (0.61) | ALDH1A1GAASMN1; SMN2MAPTHTT | |
| SCHEMBL8127349 | 0.70 | FLT1 (0.35) | ALDH1A1GAASMN1; SMN2FFAR4TSHR | |
| SCHEMBL8121462 | 0.65 | ALDH1A1 (0.38) | ALDH1A1GAASMN1; SMN2MAPTMEN1 | |
| SCHEMBL7680981 | 0.64 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2MAPK1MAPTHTT | |
| SCHEMBL2788247 | 0.63 | CA1 (0.70) | ALDH1A1GAASMN1; SMN2MAPK1IDO1 | |
| SCHEMBL14950837 | 0.60 | ALDH1A1 (0.66) | ALDH1A1GAASMN1; SMN2MAPK1MAPT | |
| SCHEMBL10449140 | 0.59 | CA1 (0.63) | ALDH1A1GAASMN1; SMN2MAPK1IDO1 | |
| SCHEMBL28429407 | 0.58 | ALDH1A1 (0.77) | ALDH1A1GAASMN1; SMN2MAPK1MAPT | |
| SCHEMBL8827169 | 0.58 | HTT (0.67) | ALDH1A1GAAHTTIDO1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |