Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.78 |
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.72 |
| ▸ | MEN1 | O00255 | 8/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | HTT | P42858 | 3/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | DDX3X | O00571 | 1/20 | 0.71 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22737807 | 0.88 | MAPT (0.68) | MAPTLMNAKMT2AMEN1NPSR1 | |
| SCHEMBL14438981 | 0.88 | MEN1 (0.78) | MAPTLMNAKMT2AMEN1NPSR1 | |
| SCHEMBL11807869 | 0.84 | NPSR1 (0.93) | MAPTLMNAKMT2AMEN1NPSR1 | |
| SCHEMBL13380966 | 0.84 | DDX3X (1.00) | MAPTLMNAKMT2AMEN1NPSR1 | |
| SCHEMBL22737384 | 0.82 | MAPT (0.70) | MAPTLMNAKMT2AMEN1NPSR1 | |
| SCHEMBL13380962 | 0.81 | DDX3X (0.93) | MAPTLMNAKMT2AMEN1NPSR1 | |
| SCHEMBL23345459 | 0.81 | KMT2A (0.72) | MAPTLMNAKMT2AMEN1NPSR1 | |
| SCHEMBL3813156 | 0.80 | MAPT (0.66) | MAPTLMNAKMT2AMEN1NPSR1 | |
| SCHEMBL11918184 | 0.80 | MAPT (0.65) | MAPTLMNAKMT2AMEN1NPSR1 | |
| SCHEMBL12417187 | 0.80 | MAPT (0.65) | MAPTLMNAKMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335339-B1 | PREVENTING HEPATITIS B INFECTION WITH VIRICIDE | SCRIPTGEN PHARMACEUTICALS, INC. | 2002-01-01 | — | — | US | claimed |