Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 4/20 | 0.93 |
| ▸ | MAPT | P10636 | 4/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | CA12 | O43570 | 8/20 | 0.68 |
| ▸ | CA1 | P00915 | 8/20 | 0.68 |
| ▸ | CA2 | P00918 | 8/20 | 0.68 |
| ▸ | CA9 | Q16790 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13380966 | 0.97 | DDX3X (1.00) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL8908392 | 0.89 | DDX3X (0.85) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL8909166 | 0.89 | DDX3X (0.85) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL11913707 | 0.85 | DDX3X (0.69) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL13380954 | 0.85 | MAPT (1.00) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL8238843 | 0.81 | DDX3X (0.68) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL7689352 | 0.81 | MAPT (0.78) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL7696169 | 0.80 | DDX3X (0.69) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL7696168 | 0.80 | DDX3X (0.69) | DDX3XMAPTMEN1KMT2AHTT | |
| SCHEMBL22737807 | 0.79 | MAPT (0.68) | DDX3XMAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-04-01 | — | — | US | disclosed |
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | HMOX1, HMOX2, PPOX | DDX3X 1391/4885MAPT 3791/4885MEN1 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.