Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665513 | 0.98 | L3MBTL1 (0.61) | L3MBTL1PPARGHDAC1HTR1BKDM4E | |
| SCHEMBL16902858 | 0.86 | TDP1 (0.73) | PPARGHDAC1KDM4EMAPK1TDP1 | |
| SCHEMBL16902870 | 0.86 | TDP1 (0.73) | PPARGHDAC1KDM4EMAPK1TDP1 | |
| SCHEMBL16902865 | 0.86 | TDP1 (0.73) | PPARGHDAC1KDM4EMAPK1TDP1 | |
| SCHEMBL16902856 | 0.86 | TDP1 (0.73) | PPARGHDAC1KDM4EMAPK1TDP1 | |
| SCHEMBL16902859 | 0.86 | TDP1 (0.73) | PPARGHDAC1KDM4EMAPK1TDP1 | |
| SCHEMBL16902850 | 0.86 | TDP1 (0.73) | PPARGHDAC1KDM4EMAPK1TDP1 | |
| SCHEMBL16902857 | 0.86 | TDP1 (0.73) | PPARGHDAC1KDM4EMAPK1TDP1 | |
| SCHEMBL16902871 | 0.86 | TDP1 (0.73) | PPARGHDAC1KDM4EMAPK1TDP1 | |
| SCHEMBL7695787 | 0.84 | L3MBTL1 (0.51) | L3MBTL1PPARGHDAC1HTR1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024619-A1 | AMINE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 2002-03-28 | — | — | WO | disclosed |