Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689751 | 0.88 | HPGD (0.51) | HSP90AA1HSP90AB1HPGDMAP1LC3BALDH1A1 | |
| SCHEMBL7690465 | 0.85 | TP53 (0.46) | HSP90AA1HSP90AB1HPGDALDH1A1TSHR | |
| SCHEMBL6796888 | 0.82 | ALPL (0.41) | HSP90AA1HSP90AB1HPGDALPLMEN1 | |
| SCHEMBL7685559 | 0.81 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1HPGDMAP1LC3BALDH1A1 | |
| SCHEMBL7680811 | 0.81 | — | — | |
| SCHEMBL1781303 | 0.79 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1HPGDMAP1LC3BALDH1A1 | |
| SCHEMBL7689152 | 0.77 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1HPGDALDH1A1TSHR | |
| SCHEMBL27549204 | 0.76 | TRPV1 (0.35) | ALDH1A1KMT2AADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7689463 | 0.74 | — | — | |
| SCHEMBL1781095 | 0.72 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1HPGDMAP1LC3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |