Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.38 |
| ▸ | SLC9A2 | Q9UBY0 | 4/20 | 0.38 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689751 | 0.83 | HPGD (0.51) | MEN1KMT2AHSP90AA1HSP90AB1HPGD | |
| SCHEMBL6804541 | 0.82 | ALPL (0.41) | ALPLSLC9A1SLC9A2SLC9A3 | |
| SCHEMBL7689622 | 0.82 | HSP90AA1 (0.41) | ALPLMEN1KMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL7681338 | 0.81 | ALPL (0.41) | ALPLSLC9A1SLC9A2SLC9A3 | |
| SCHEMBL7690465 | 0.77 | TP53 (0.46) | HSP90AA1HSP90AB1HPGD | |
| SCHEMBL7685559 | 0.76 | HSP90AA1 (0.61) | ALPLMEN1KMT2AHSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL6804928 | 0.74 | SLC9A1 (0.44) | SLC9A1SLC9A2SLC9A3 | |
| Hydrochloric Acid SCHEMBL6804933 | 0.74 | SLC9A1 (0.44) | SLC9A1SLC9A2SLC9A3 | |
| SCHEMBL12958096 | 0.74 | SLC9A1 (0.45) | SLC9A1SLC9A2SLC9A3 | |
| SCHEMBL6795178 | 0.73 | ALPL (0.41) | ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706732-B1 | PROPHYLACTIC AND THERAPEUTIC EFFECT ON MYOCARDIAL INFARCTION AND ACCOMPANYING DYSFUNCTIONS, ARRHYTHMIA, UNSTABLE ANGINA, CARDIAC HYPERTROPHY, ETC.; SODIUM-PROTON EXCHANGE INHIBITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-03-16 | — | — | US | disclosed |
| EP-1182194-A1 | PERNASAL PREPARATIONS | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |