Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1225548 | 1.00 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2GAABACE1 | |
| SCHEMBL30483952 | 0.91 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2EPHX2LMNA | |
| Mannitol SCHEMBL29038510 | 0.84 | ALDH1A1 (0.47) | NPC1RAB9ASMN1; SMN2GAAEPHX2 | |
| SCHEMBL7148071 | 0.83 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2GAABACE1 | |
| SCHEMBL18992673 | 0.82 | THRB (0.61) | NPC1RAB9ASMN1; SMN2EPHX2KMT2A | |
| SCHEMBL30809838 | 0.82 | ATM (0.60) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL3465056 | 0.81 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2GAABACE1 | |
| SCHEMBL6154030 | 0.81 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2GAABACE1 | |
| SCHEMBL20234449 | 0.80 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2GAABACE1 | |
| SCHEMBL19334001 | 0.79 | SMN1; SMN2 (0.62) | NPC1RAB9ASMN1; SMN2GAABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428665-B | Method for producing (meth) acrylic ester | 东亚合成株式会社 | 2021-10-15 | — | — | CN | disclosed |
| CN-107406363-B | Method for producing (meth) acrylic ester | 东亚合成株式会社 | 2021-10-08 | — | — | CN | disclosed |
| CN-107709377-B | Curable composition | 东亚合成株式会社 | 2021-04-20 | — | — | CN | disclosed |
| CN-107709376-B | Curable composition | 东亚合成株式会社 | 2020-10-30 | — | — | CN | disclosed |
| CN-107922555-B | Curable composition | 东亚合成株式会社 | 2020-08-28 | — | — | CN | disclosed |
| EP-0922700-B1 | Metal chelates of macrocyclic polyaminocarboxylic derivatives and their use for the diagnostic imaging | GUERBET SA (FR) | 2002-09-11 | — | — | EP | disclosed |
| US-6187285-B1 | IN PARTICULAR MAGNETIC RESONANCE IMAGING (MRI) FOR MAGNETIC CATIONS. | GUERBET (FR) | 2001-02-13 | — | — | US | disclosed |
| WO-2000000461-A1 | TETRAIODOTEREPHTHALAMIDE POLYHYDROXYLATED DERIVATIVES, PREPARATION METHOD AND USE IN RADIOLOGY | GUERBET S.A. (FR) | 2000-01-06 | — | — | WO | disclosed |
| EP-0922700-A1 | Metal chelates of macrocyclic polyaminocarboxylic derivatives and their use for the diagnostic imaging | GUERBET (FR) | 1999-06-16 | — | — | EP | disclosed |