SCHEMBL768969

SCHEMBL768969

CCCCC(CC)COC(=C=O)Cc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
MAPK1 P28482 3/20 0.37
LMNA P02545 2/20 0.33
CA2 P00918 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
GAA P10253 1/20 0.30
XBP1 P17861 1/20 0.30
ATM Q13315 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20835341 0.91 ALDH1A1 (0.40) ALDH1A1MAPK1LMNACA2CYP3A4
SCHEMBL28974096 0.91 ALDH1A1 (0.34) ALDH1A1MAPK1PRSS1PRSS2PRSS3
SCHEMBL19834895 0.90 ALDH1A1 (0.44) ALDH1A1MAPK1LMNACA2CYP3A4
SCHEMBL5549692 0.86 EPHX2 (0.31)
SCHEMBL76644 0.85 ALDH1A1 (0.43) ALDH1A1MAPK1LMNACA2CYP3A4
SCHEMBL29496845 0.85 ALDH1A1 (0.43) ALDH1A1MAPK1LMNACA2CYP3A4
SCHEMBL31631277 0.83 ALDH1A1 (0.36) ALDH1A1MAPK1LMNACA2CYP3A4
SCHEMBL6832924 0.83 RXFP1 (0.34) ALDH1A1
SCHEMBL6245434 0.83
SCHEMBL7072419 0.82 ALDH1A1 (0.41) ALDH1A1MAPK1LMNACA2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 575 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12522534-B2 Self-healing optical fibers and the compositions used to create the same COVESTRO (NETHERLANDS) B.V. (NL) 2026-01-13 US disclosed
US-12491704-B2 Multi-layered optical devices COVESTRO (NETHERLANDS) B.V. (NL) 2025-12-09 US disclosed
US-20250346751-A1 ACRYLONITRILE STYRENE ACRYLATE COPOLYMER COMPOSITION WITH IMPROVED UV RESISTANCE INEOS STYROLUTION GROUP GMBH (DE) 2025-11-13 US disclosed
EP-3941970-B1 UV CURABLE COMPOSITIONS FOR DIRT PICK-UP RESISTANCE BASF SE (DE) 2025-10-15 EP disclosed
US-12426670-B2 Midsole structure of an article of footwear including mesh NIKE, INC. (US) 2025-09-30 US disclosed
EP-4008210-B1 A KNIT TEXTILE NIKE INNOVATE CV (US) 2025-08-27 EP disclosed
US-20250251531-A1 LOW-VOLATILITY RADIATION CURABLE COMPOSITIONS FOR COATING OPTICAL FIBERS COVESTRO LLC 2025-08-07 US disclosed
US-12342902-B2 Footwear sole structure having a composite element and methods for manufacturing same NIKE, INC. (US) 2025-07-01 US disclosed
EP-3538699-B1 KNIT ARTICLES AND PROCESSES FOR MAKING THE SAME NIKE INNOVATE CV (US) 2025-05-07 EP disclosed
EP-3841166-B2 STABILIZED ROTOMOLDED POLYOLEFIN BASF SE (DE) 2025-05-07 EP disclosed
US-20020106413-A1 Mixtures of phenolic and inorganic materials with antimicrobial activity CIBA CORPORATION 2002-08-08 US disclosed
US-20020086924-A1 Stabilized gamma irradiated polyolefins CIBA SPECIALTY CHEMICALS CORP. 2002-07-04 US disclosed
EP-1171890-A1 STABILIZED TELECOMMUNICATION CABLE INSULATION COMPOSITION Ciba SC Holding AG (CH) 2002-01-16 EP disclosed
US-20020002242-A1 Hyperbranched amphiphilic polymeric additives and polymer compositions with increased surface energy CIBA SPECIALTY CHEMICALS CORP. 2002-01-03 US disclosed
US-20010047046-A1 Polyolefin film compositions with permanent antifog properties TECHMER PM, LLC 2001-11-29 US disclosed
EP-1152027-A1 Polyolefin film compositions with permanent antifog properties Ciba SC Holding AG (CH) 2001-11-07 EP disclosed
EP-1106627-A1 Novel phosphine oxide photoinitiator systems and curable compositions with low color Ciba SC Holding AG (CH) 2001-06-13 EP disclosed
US-6228495-B1 MIXTURE OF POLYOLEFIN AND ANTIOXIDANT CIBA SPECIALTY CHEMICALS CORPORATION 2001-05-08 US disclosed
WO-2000058975-A1 STABILIZED TELECOMMUNICATION CABLE INSULATION COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-10-05 WO disclosed
EP-1038912-A2 High molecular weight hindered hydrocarbyloxyamine stabilizers Ciba SC Holding AG (CH) 2000-09-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020106413-A1 Mixtures of phenolic and inorganic materials with antimicrobial activity CUTA, PUF60, TYR ALDH1A1 2607/4885MAPK1 255/4885LMNA 1657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.