Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | GUSB | P08236 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706578 | 0.87 | GAA (0.67) | ALDH1A1SMN1; SMN2KDM4EGAAKMT2A | |
| SCHEMBL7694783 | 0.84 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2KDM4EGUSBGAA | |
| SCHEMBL31705162 | 0.84 | NPSR1 (0.64) | ALDH1A1SMN1; SMN2KDM4EGAANPC1 | |
| SCHEMBL7695710 | 0.83 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2KDM4EGUSBGAA | |
| SCHEMBL31541537 | 0.82 | GUSB (0.64) | ALDH1A1SMN1; SMN2KDM4EGUSBKMT2A | |
| SCHEMBL10112940 | 0.81 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2KDM4EGUSBGAA | |
| SCHEMBL10280173 | 0.81 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2KDM4EGUSBGAA | |
| SCHEMBL10112932 | 0.81 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2KDM4EGUSBGAA | |
| SCHEMBL7697747 | 0.81 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KDM4EGUSBGAA | |
| SCHEMBL16497679 | 0.81 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2KDM4EGUSBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | claimed |