Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.64 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | P4HB | P07237 | 3/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689781 | 1.00 | PDCD1 (0.64) | PDCD1CD274MAPTALDH1A1KMT2A | |
| SCHEMBL1553872 | 0.82 | MAPT (0.58) | PDCD1CD274MAPTALDH1A1KMT2A | |
| SCHEMBL1553869 | 0.82 | MAPT (0.58) | PDCD1CD274MAPTALDH1A1KMT2A | |
| SCHEMBL7417299 | 0.79 | PDCD1 (0.74) | PDCD1CD274MAPTALDH1A1KMT2A | |
| SCHEMBL21457289 | 0.78 | PDCD1 (1.00) | PDCD1CD274MAPTALDH1A1KMT2A | |
| SCHEMBL21457292 | 0.78 | PDCD1 (1.00) | PDCD1CD274MAPTALDH1A1KMT2A | |
| SCHEMBL10848993 | 0.77 | PDCD1 (0.71) | PDCD1CD274MAPTALDH1A1KMT2A | |
| SCHEMBL10375509 | 0.77 | PDCD1 (0.71) | PDCD1CD274MAPTALDH1A1KMT2A | |
| SCHEMBL1695615 | 0.73 | CA12 (0.47) | MAPTALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL8871187 | 0.72 | KMT2A (0.45) | MAPTALDH1A1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399627-B1 | ANTICOAGULANTS; PROTHROMINASE, SERINE PROTEASE INHIBITOR; ACRYLAMIDE DERIVATIVES | COR THERAPEUTICS, INC. | 2002-06-04 | — | — | US | disclosed |
| EP-1159264-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000047554-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2000-08-17 | — | — | WO | disclosed |