Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20366937 | 0.86 | THRB (0.51) | TSHRALDH1A1LMNATP53POLB | |
| SCHEMBL8076395 | 0.84 | PPARG (0.53) | TSHRALDH1A1LMNANPC1RAB9A | |
| SCHEMBL8063792 | 0.84 | PPARG (0.53) | TSHRALDH1A1LMNANPC1RAB9A | |
| SCHEMBL8072402 | 0.84 | PPARG (0.53) | TSHRALDH1A1LMNANPC1RAB9A | |
| SCHEMBL8424812 | 0.81 | PPARG (0.52) | TSHRALDH1A1TP53L3MBTL1TDP1 | |
| SCHEMBL7689137 | 0.80 | TAS1R3 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7674813 | 0.80 | TAS1R3 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7685263 | 0.79 | ATM (0.54) | ALDH1A1LMNAKDM4EHDAC3HDAC4 | |
| SCHEMBL7672412 | 0.79 | EPHX2 (0.43) | TSHRALDH1A1LMNA | |
| SCHEMBL7672042 | 0.79 | PTPN1 (0.44) | TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348614-B1 | PROTECTING CROPS AGAINST PLANT DISEASES | AGROGENE LTD. (IL) | 2002-02-19 | — | — | US | claimed |
| EP-0948481-A1 | AMINOBUTYRIC ACID FUNGICIDES | Agrogene Ltd. (IL) | 1999-10-13 | — | — | EP | claimed |
| WO-1998029387-A1 | AMINOBUTYRIC ACID FUNGICIDES | AGROGENE LTD. (IL) | 1998-07-09 | — | — | WO | claimed |
| US-6348614-B1 | PROTECTING CROPS AGAINST PLANT DISEASES | AGROGENE LTD. (IL) | 2002-02-19 | — | — | US | disclosed |
| EP-0948481-A1 | AMINOBUTYRIC ACID FUNGICIDES | Agrogene Ltd. (IL) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998029387-A1 | AMINOBUTYRIC ACID FUNGICIDES | AGROGENE LTD. (IL) | 1998-07-09 | — | — | WO | disclosed |