Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24830044 | 0.85 | NPC1 (0.71) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL31184229 | 0.85 | NPC1 (0.71) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL29832726 | 0.85 | NPC1 (0.71) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL7697600 | 0.84 | MAPT (0.74) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL7694046 | 0.84 | NPC1 (0.51) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL1442062 | 0.81 | HTT (0.57) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL1443423 | 0.81 | HTT (0.57) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL3091537 | 0.81 | PIK3CA (0.55) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL7693429 | 0.81 | HTR3A (0.74) | MAPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL7699332 | 0.80 | MAPT (0.51) | MAPTALDH1A1NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |