Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 5/20 | 0.48 |
| ▸ | NOS1 | P29475 | 5/20 | 0.48 |
| ▸ | NOS2 | P35228 | 3/20 | 0.48 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692254 | 0.90 | NOS3 (0.52) | NOS3NOS1NOS2 | |
| SCHEMBL7701797 | 0.82 | NOS3 (0.48) | NOS3NOS1NOS2QRFPR | |
| SCHEMBL7696502 | 0.81 | NOS1 (0.52) | NOS3NOS1NOS2 | |
| SCHEMBL7690814 | 0.81 | QRFPR (0.50) | NOS3NOS1NOS2QRFPR | |
| SCHEMBL7564087 | 0.81 | QRFPR (0.66) | NOS3NOS1NOS2QRFPR | |
| Hydrochloric Acid SCHEMBL7563787 | 0.80 | QRFPR (0.64) | NOS3NOS1NOS2QRFPR | |
| SCHEMBL7570370 | 0.78 | QRFPR (0.52) | NOS3NOS1NOS2QRFPR | |
| SCHEMBL7564022 | 0.77 | QRFPR (0.51) | NOS3NOS1NOS2QRFPR | |
| SCHEMBL7566514 | 0.77 | QRFPR (0.51) | NOS3NOS1NOS2QRFPR | |
| Hydrochloric Acid SCHEMBL7562399 | 0.76 | QRFPR (0.50) | NOS3NOS1NOS2QRFPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020511-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2002-03-14 | — | — | WO | claimed |