Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 4/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697732 | 0.82 | LCK (0.58) | LMNAMAPTTAAR1CSNK2A2CSNK2A1 | |
| SCHEMBL7700675 | 0.78 | MAPK14 (0.43) | LMNAMAPTGBA1KDM4EALDH1A1 | |
| SCHEMBL4864860 | 0.76 | LMNA (0.65) | LMNAMAPTGBA1CSNK2A2CSNK2A1 | |
| SCHEMBL3906108 | 0.76 | L3MBTL1 (0.66) | LMNAMAPTTAAR1NOS1NOS3 | |
| SCHEMBL4857481 | 0.75 | LMNA (0.64) | LMNAMAPTGBA1CSNK2A2CSNK2A1 | |
| SCHEMBL4856772 | 0.75 | GBA1 (0.82) | LMNAMAPTGBA1KDM4EAPP | |
| SCHEMBL6307693 | 0.74 | GLP1R (0.57) | LMNAMAPTGBA1TAAR1CSNK2A2 | |
| SCHEMBL7699335 | 0.73 | ACP1 (0.55) | MAPTKDM4EMEN1HTTKMT2A | |
| SCHEMBL4866463 | 0.73 | LMNA (0.61) | LMNAMAPTGBA1CSNK2A2CSNK2A1 | |
| SCHEMBL5104398 | 0.73 | CCNE2 (0.63) | LMNAMAPTGBA1CSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | claimed |
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |