Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697114 | 0.83 | EPHX2 (0.54) | ALDH1A1ALOX12TP53GAAMAPT | |
| SCHEMBL7693786 | 0.82 | CA12 (0.69) | ALDH1A1ALOX12GAAMAPTCA12 | |
| SCHEMBL7690425 | 0.80 | ALDH1A1 (0.63) | ALDH1A1ALOX12TP53GAAMAPT | |
| SCHEMBL7693844 | 0.76 | ALDH1A1 (0.58) | ALDH1A1ALOX12TP53GAAMAPT | |
| SCHEMBL7689567 | 0.76 | EPHX2 (0.52) | ALDH1A1ALOX12TP53GAAMAPT | |
| SCHEMBL7696433 | 0.74 | ALDH1A1 (0.58) | ALDH1A1ALOX12TP53GAAMAPT | |
| SCHEMBL10112998 | 0.74 | CA12 (0.73) | ALDH1A1ALOX12GAAMAPTCA12 | |
| SCHEMBL7688985 | 0.71 | ALDH1A1 (0.46) | ALDH1A1ALOX12TP53GAAMAPT | |
| SCHEMBL7695170 | 0.70 | ALDH1A1 (0.43) | ALDH1A1ALOX12TP53GAAMAPT | |
| SCHEMBL10113038 | 0.70 | CA1 (0.59) | ALDH1A1ALOX12TP53GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |