Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 19/20 | 0.76 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471121 | 1.00 | TBXAS1 (0.76) | TBXAS1TBXA2RHDAC3HDAC4HDAC1 | |
| SCHEMBL10470554 | 0.98 | TBXAS1 (0.75) | TBXAS1TBXA2R | |
| SCHEMBL3159035 | 0.93 | TBXAS1 (0.74) | TBXAS1TBXA2R | |
| SCHEMBL10680940 | 0.87 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL10620921 | 0.87 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL10634966 | 0.87 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL10616364 | 0.87 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL10634973 | 0.87 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL10616376 | 0.87 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| (E)-Isbogrel SCHEMBL4060 | 0.85 | TBXAS1 (1.00) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017684-B1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| EP-1017684-A1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-12 | — | — | EP | disclosed |
| US-6083479-A | Contrast media for infarction and necrosis imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-04 | — | — | US | disclosed |
| WO-1999016757-A1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-04-08 | — | — | WO | disclosed |
| US-4927838-A | CARDIOVASCULAR DISORDERS | HOFFMAN-LA ROCHE INC. (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0298466-A2 | Substituted alkene carboxylic acid amides and derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-11 | — | — | EP | disclosed |