Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471121 | 0.98 | TBXAS1 (0.76) | TBXAS1TBXA2R | |
| SCHEMBL7690245 | 0.98 | TBXAS1 (0.76) | TBXAS1TBXA2R | |
| SCHEMBL3159035 | 0.94 | TBXAS1 (0.74) | TBXAS1TBXA2R | |
| (E)-Isbogrel SCHEMBL4060 | 0.87 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| Isbogrel SCHEMBL7766547 | 0.87 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| (E)-Isbogrel SCHEMBL4061 | 0.87 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL2377776 | 0.86 | TBXAS1 (0.73) | TBXAS1TBXA2R | |
| (E)-Isbogrel SCHEMBL10632111 | 0.85 | TBXAS1 (0.97) | TBXAS1TBXA2R | |
| Isbogrel SCHEMBL10632116 | 0.85 | TBXAS1 (0.97) | TBXAS1TBXA2R | |
| SCHEMBL10634973 | 0.85 | TBXAS1 (1.00) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927838-A | CARDIOVASCULAR DISORDERS | HOFFMAN-LA ROCHE INC. (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0298466-A2 | Substituted alkene carboxylic acid amides and derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-11 | — | — | EP | disclosed |