Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 14/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047957 | 0.71 | AKR1C2 (0.51) | ALDH1A1CYP3A4TSHRRECQLHSD17B10 | |
| SCHEMBL29617335 | 0.71 | AKR1C2 (0.51) | ALDH1A1CYP3A4TSHRRECQLHSD17B10 | |
| SCHEMBL5465843 | 0.71 | AAK1 (0.35) | EGFRERBB2CYP3A4 | |
| SCHEMBL7691286 | 0.70 | MAPK1 (0.42) | ALDH1A1CYP3A4TSHRRECQLHSD17B10 | |
| SCHEMBL1340231 | 0.69 | ALDH1A1 (0.56) | EGFRERBB2ALDH1A1CYP3A4TSHR | |
| SCHEMBL30083634 | 0.69 | EGFR (0.40) | SRCEGFRERBB2ALDH1A1ABL1 | |
| SCHEMBL6642503 | 0.69 | EGFR (0.40) | SRCEGFRERBB2ALDH1A1ABL1 | |
| SCHEMBL7047960 | 0.68 | AKR1C4 (0.37) | ALDH1A1CYP3A4TSHRRECQLHSD17B10 | |
| SCHEMBL7066659 | 0.68 | PARP1 (0.38) | SRCEGFRERBB2 | |
| SCHEMBL16636889 | 0.67 | SRC (0.40) | SRCEGFRERBB2ALDH1A1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748799-B1 | PROCESS FOR PRODUCING 5,7-DICHLORO-4-HYDROXYQUINOLINE | ISHIHARA SANGYO KAISHA (JP) | 2002-09-11 | — | — | EP | claimed |
| EP-0748799-A1 | PROCESS FOR PRODUCING 5,7-DICHLORO-4-HYDROXYQUINOLINE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-12-18 | — | — | EP | claimed |
| EP-0748799-B1 | PROCESS FOR PRODUCING 5,7-DICHLORO-4-HYDROXYQUINOLINE | ISHIHARA SANGYO KAISHA (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5731440-A | Intermediates for producing 5,7-dichloro-4-hydroxyquinoline | ISHIHARA SANGYO KAISHA LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0748799-A1 | PROCESS FOR PRODUCING 5,7-DICHLORO-4-HYDROXYQUINOLINE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-12-18 | — | — | EP | disclosed |