Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683709 | 0.93 | ALDH1A1 (0.35) | FFAR4KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7689761 | 0.92 | FFAR4 (0.35) | FFAR4KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7690259 | 0.91 | FFAR4 (0.35) | FFAR4KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7688314 | 0.90 | FFAR4 (0.35) | FFAR4KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7681535 | 0.89 | GRM2 (0.32) | FFAR4KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7621679 | 0.88 | FNTA (0.37) | KDM4EALDH1A1HTTSMN1; SMN2SCN9A | |
| SCHEMBL7690278 | 0.88 | FFAR4 (0.36) | FFAR4KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7685752 | 0.87 | HTT (0.42) | FFAR4KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7683737 | 0.85 | KDM4E (0.39) | FFAR4KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7626194 | 0.82 | CBX7 (0.39) | KDM4EALDH1A1HTTSMN1; SMN2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052363-A1 | Inhibitors of prenyl-protein transferase | DINSMORE CHRISTOPHER J (US) | 2002-05-02 | — | — | US | claimed |
| WO-2001060369-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-08-23 | — | — | WO | claimed |
| US-20020052363-A1 | Inhibitors of prenyl-protein transferase | DINSMORE CHRISTOPHER J (US) | 2002-05-02 | — | — | US | disclosed |
| WO-2001060369-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052363-A1 | Inhibitors of prenyl-protein transferase | FNTA, FNTB, PTAR1 | FFAR4 4314/4885KDM4E 2677/4885ALDH1A1 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.