Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690737 | 1.00 | MAPT (0.61) | MAPTKDM4EALDH1A1L3MBTL1CA12 | |
| SCHEMBL17885979 | 0.87 | MAPT (0.65) | MAPTKDM4EKMT2ALMNANPC1 | |
| SCHEMBL8410290 | 0.86 | FDPS (0.58) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL8410287 | 0.86 | FDPS (0.58) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL16133525 | 0.85 | MAPT (0.58) | MAPTKDM4ECA12CA1CA2 | |
| SCHEMBL21190009 | 0.85 | MAPT (0.62) | MAPTKDM4EALDH1A1CA12CA1 | |
| SCHEMBL28981013 | 0.84 | MAPT (0.57) | MAPTKDM4ECA12CA1CA2 | |
| SCHEMBL16133524 | 0.84 | MAPT (0.57) | MAPTKDM4ECA12CA1CA2 | |
| SCHEMBL16133523 | 0.84 | MAPT (0.57) | MAPTKDM4ECA12CA1CA2 | |
| SCHEMBL18288746 | 0.84 | MAPT (0.71) | MAPTKDM4EALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335409-B1 | LIQUID CRYSTAL ORIENTATION | ROLIC AG (CH) | 2002-01-01 | — | — | US | disclosed |
| US-6107427-A | Cross-linkable, photoactive polymer materials | ROLIC AG (CH) | 2000-08-22 | — | — | US | disclosed |