Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410287 | 1.00 | FDPS (0.58) | FDPSKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13164753 | 0.88 | FDPS (0.59) | FDPSKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13164750 | 0.87 | CA12 (0.56) | FDPSKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13164751 | 0.87 | CA12 (0.56) | FDPSKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7690737 | 0.86 | MAPT (0.61) | FDPSKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL7690738 | 0.86 | MAPT (0.61) | FDPSKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL31580174 | 0.86 | FDPS (0.58) | FDPSKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL21880898 | 0.85 | FDPS (0.55) | FDPSKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL12947702 | 0.85 | TNFRSF1A (0.64) | FDPSKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7691364 | 0.85 | FDPS (0.57) | FDPSKDM4EMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965761-A | CROSSLINKABLE SILANE DERIVAATIVES HAVING A 3-ARYLACRYLIC ACID OR-ACRYLAMIDE GROUP FOR ORIENTING LAYER AND FOR NONSTRUCTURED AND STRUCTURED OPTICAL ELEMENTS AND MULTILAYER SYSTEMS; PHOTOSTABILITY; CONTRAST; RESOLUTION | ROLIC AG (CH) | 1999-10-12 | — | — | US | disclosed |